The Sinclair Method:
The Fourth Option
for Alcohol Recovery
Most people are told to quit alone, go to AA, or enter rehab. Sinclair Method Guide explains the science-based medication option many people never hear about.
Learn how naltrexone, alcohol reinforcement, and pharmacological extinction are changing the way people think about alcohol recovery.
Most people are given three options.
There is a fourth.
Alcohol recovery is most often framed around willpower, meetings, or rehab. But there is a science-based, medication-assisted approach that many people never hear about.
Willpower / Quitting Alone
Trying to moderate or quit using self-control alone.
AA / Peer Support
Abstinence-focused peer support and community-based recovery.
Rehab / Intensive Treatment
Structured treatment — sometimes necessary, often expensive and disruptive.
The Sinclair Method
Medication-assisted alcohol reduction using naltrexone to gradually reduce alcohol reward and reinforcement over time.
"The goal of this site is simple: make the fourth option easier to understand and harder to ignore."
Start Here
New to the Sinclair Method? These are the most important questions to understand first.
Alcohol use disorder is not a moral failure.
It is a brain chemistry problem.
Problem drinking involves reward reinforcement, cravings, habit loops, and learned associations in the brain. The Sinclair Method targets alcohol reward directly — using naltrexone to gradually reduce the reinforcement that drives drinking over time.
This process is called pharmacological extinction — and it is the scientific foundation of the Sinclair Method.
Learn about pharmacological extinction
The Sinclair Method is not just another recovery tactic.
It is a different model of the problem.
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Everything on this site is organized around the questions real people ask about alcohol, naltrexone, and the Sinclair Method.
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A plain-English guide to understanding naltrexone, alcohol cravings, pharmacological extinction, and the questions to ask before speaking with a licensed clinician.
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Educational Information Only
This site is for education only and is not a substitute for medical advice, diagnosis, or treatment. Always speak with a qualified, licensed clinician before making any decisions about medication or treatment. Naltrexone is a prescription medication and is not appropriate for everyone.
Need Immediate Help?
If you are in immediate danger, call 911. For substance use support in the United States, contact SAMHSA's National Helpline: 1-800-662-HELP (4357) — free, confidential, 24/7.